Unique Variations of pbp2b Sequences in Penicillin-Nonsusceptible Streptococcus pneumoniae Isolates from Korea

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Unique variations of pbp2b sequences in penicillin-nonsusceptible Streptococcus pneumoniae isolates from Korea.

pbp2b gene alterations were analyzed in 102 clinical isolates of Streptococcus pneumoniae (30 penicillin susceptible, 23 intermediate, and 49 resistant) from Korea. On the basis of PBP2B amino acid sequences, penicillin-nonsusceptible isolates of S. pneumoniae belonged to six groups, and 76% of the isolates in groups I to IV showed the same divergent block of amino acid alterations. Thirteen is...

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differentiation of penicillin susceptible and nonsusceptible streptococcus pneumoniae

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2004

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.42.4.1746-1750.2004